Sodobna radioterapija stavi na število 5
Modern radiotherapy
all-in on number 5 - no more bets!
DOI:
https://doi.org/10.25670/oi2025-001onKeywords:
radiotherapy, 5-fractions, cancer, quality-of-life, optimisationAbstract
Razvoj sodobne radioterapije poteka popolnoma v skladu z načelom Citius, Altius, Fortius (hitreje, višje, močneje), hkrati pa sledi tudi filozofiji »manj je več«. V zadnjih letih se je režim radioterapije v petih frakcijah pokazal kot inovativen pristop, ki ponuja krajše zdravljenje, večjo natančnost in boljšo terapevtsko učinkovitost, ob tem pa zmanjšuje porabo sredstev namenjenih za zdravljenje. Dokazi iz obsežnih prospektivnih študij so potrdili učinkovitost tega pristopa pri zdravljenju raka dojke, prostate, pljuč in danke ter pri zdravljenju oligometastatske bolezni. Poleg tega je bil tehnološki napredek na področju slikanja, stereotaktičnih tehnik in samega obsevanja ključnega pomena za zagotavljanje varnosti ter natančnosti tega zdravljenja. Poleg klinične učinkovitosti so prednosti obsevanja v petih frakcijah tudi izboljšanje kakovosti življenja bolnikov, zmanjšanje bremena zdravljenja in povečanje učinkovitosti zdravstvenega varstva. V dobi sodobne radioterapije prevladuje Citius, Altius, Fortius – ker manj pomeni več, prihodnost pa je zdaj.
Abstract (Eng)
The evolution of modern radiotherapy aligns seamlessly with the principles of Citius, Altius, Fortius—faster, higher, stronger— while embracing the Less is More philosophy. In recent years, the 5-fraction radiotherapy regimen has emerged as a transformative approach, offering shorter treatment durations, higher precision, and enhanced therapeutic efficacy, all while optimizing healthcare resources. Evidence from large prospective trials has confirmed its efficacy in breast, prostate, lung, and rectal cancers, as well as in the management of oligometastatic disease. Furthermore, technological advancements in imaging, stereotactic techniques, and dose delivery have played a crucial role in ensuring the safety and precision of these treatments. Beyond clinical efficacy, the benefits of 5-fraction radiotherapy extend to improving patient quality of life, reducing treatment burden, and enhancing healthcare efficiency. In the era of modern radiotherapy, Citius, Altius, Fortius prevails—because Less is More, and the future is now.
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Copyright (c) 2025 Angel Montero-Luis, Ivica Ratoša , Helena Barbara Zobec Logar
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